Glucuronidation
REACTOME PATHWAYThe Glucuronidation pathway (Reactome ID: R-HSA-156588) involves 7 genes and is affected by 12 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Glucuronidation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | scutellarein | — | 113 |
| 2 | celastrol | — | 300 |
| 3 | Pueraria | — | 300 |
| 4 | Thyroxine | — | 994 |
| 5 | Ethinyl Estradiol | — | 300 |
| 6 | Ritonavir | — | 298 |
| 7 | Thyroxine | — | 300 |
| 8 | ketoconazole | — | 299 |
| 9 | licochalcone | — | 267 |
| 10 | Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of | — | 300 |
| 11 | Edaravone | — | 298 |
| 12 | Anastrozole | — | 298 |
About the Glucuronidation Pathway
The Glucuronidation pathway is catalogued in Reactome (ID: R-HSA-156588) and involves 7 genes. In the BiohacksAI corpus, 12 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A6.