What compounds affect the Early Phase of HIV Life Cycle pathway?

29 compounds in the BiohacksAI corpus have documented interactions with genes in the Early Phase of HIV Life Cycle pathway (Reactome ID: R-HSA-162594). These compounds target 2 genes within this pathway.

What genes are in the Early Phase of HIV Life Cycle pathway?

The Early Phase of HIV Life Cycle pathway involves 2 genes. Key genes include: FEN1, PSIP1.

Early Phase of HIV Life Cycle

REACTOME PATHWAY

Reactome: R-HSA-1625942 genes29 compounds

The Early Phase of HIV Life Cycle pathway (Reactome ID: R-HSA-162594) involves 2 genes and is affected by 29 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

FEN1 PSIP1

Compounds Affecting Early Phase of HIV Life Cycle

#	Compound	Targets Hit	Studies
1	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
2	Ethidium	—	300
3	Levodopa	—	297
4	Methyldopa	—	297
5	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
6	Methylene Blue	—	200
7	Quercetin	—	300
8	Aurintricarboxylic Acid	—	184
9	Norepinephrine Precursor of epinephrine that is secreted by	—	298
10	Dequalinium	—	136
11	Diiodotyrosine	—	300
12	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
13	Epinephrine	—	299
14	Idarubicin	—	299
15	piceatannol	—	300
16	Doxycycline	—	999
17	Carmine Coloring matter from	—	300
18	Cisplatin	—	300
19	Demeclocycline	—	297
20	Dithiazanine 3-Ethyl-2-(5-(3-ethyl-2-benzothiazolinylidene)-1,3- pentadienyl)benzothiazolium.	—	135
21	Oxytetracycline	—	300
22	streptonigrin	—	299
23	Cefixime	—	300
24	Biotin	—	297
25	furylfuramide	—	82
26	Ampicillin Semi-synthetic derivative of penicillin that functions as	—	294
27	Demeclocycline	—	5
28	Edaravone	—	298
29	alphitonin [Supplementary Concept] from	—	300

About the Early Phase of HIV Life Cycle Pathway

The Early Phase of HIV Life Cycle pathway is catalogued in Reactome (ID: R-HSA-162594) and involves 2 genes. In the BiohacksAI corpus, 29 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FEN1, PSIP1.