Glycosaminoglycan metabolism
REACTOME PATHWAYThe Glycosaminoglycan metabolism pathway (Reactome ID: R-HSA-1630316) involves 5 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Glycosaminoglycan metabolism
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Hesperidin | — | 300 |
| 2 | naringin | — | 300 |
| 3 | Astemizole Antihistamine drug now withdrawn from | — | 280 |
| 4 | Labetalol | — | 295 |
| 5 | Metergoline | — | 144 |
| 6 | Methotrexate | — | 289 |
| 7 | Cyclic GMP Guanosine cyclic 3',5'-(hydrogen phosphate). | — | 300 |
| 8 | Ezetimibe | — | 296 |
| 9 | Triamcinolone | — | 300 |
About the Glycosaminoglycan metabolism Pathway
The Glycosaminoglycan metabolism pathway is catalogued in Reactome (ID: R-HSA-1630316) and involves 5 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ABCC5, CTSL, GALNS, HPSE, SLC17A5.