PKA-mediated phosphorylation of key metabolic factors
REACTOME PATHWAYThe PKA-mediated phosphorylation of key metabolic factors pathway (Reactome ID: R-HSA-163358) involves 3 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting PKA-mediated phosphorylation of key metabolic factors
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | hydroxyfasudil [Supplementary Concept] | — | 11 |
| 2 | alpelisib | — | 227 |
| 3 | Sphingosine | — | 300 |
About the PKA-mediated phosphorylation of key metabolic factors Pathway
The PKA-mediated phosphorylation of key metabolic factors pathway is catalogued in Reactome (ID: R-HSA-163358) and involves 3 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include PRKACA, PRKACB, PRKACG.