ChREBP activates metabolic gene expression
REACTOME PATHWAYThe ChREBP activates metabolic gene expression pathway (Reactome ID: R-HSA-163765) involves 2 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting ChREBP activates metabolic gene expression
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Cerulenin | — | 300 |
| 2 | Dihydroergotoxine | — | 208 |
| 3 | Hexachlorophene | — | 300 |
| 4 | egcg | — | 300 |
| 5 | Oleic Acid | — | 112 |
| 6 | gedunin | — | 54 |
| 7 | Suramin | — | 300 |
About the ChREBP activates metabolic gene expression Pathway
The ChREBP activates metabolic gene expression pathway is catalogued in Reactome (ID: R-HSA-163765) and involves 2 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FASN, PKLR.