A mixture of three different hydrogenated derivatives of ERGOTAMINE: DIHYDROERGOCORNINE; DIHYDROERGOCRISTINE; and DIHYDROERGOCRYPTINE. Dihydroergotoxine has been proposed to be a neuroprotective agent and a nootropic agent. The mechanism of its therapeutic actions is not clear, but it can act as an alpha-adrenergic antagonist and a dopamine agonist. The methanesulfonate salts of this mixture of alkaloids are called ERGOLOID MESYLATES.
Dihydroergotoxine has been studied across 25 research domains including 🧠 Focus & Attention, ❤️ Cardiovascular, 🌤️ Mood & Depression, 🧠 Neuroprotection, ⏳ Longevity & Aging. The primary research focus is 🧠 Focus & Attention with 22% of studies addressing this area.
The following compounds share molecular targets with Dihydroergotoxine, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Dihydroergotoxine is generated deterministically from 208 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.