Formation of HIV elongation complex in the absence of HIV Tat
REACTOME PATHWAYThe Formation of HIV elongation complex in the absence of HIV Tat pathway (Reactome ID: R-HSA-167152) involves 4 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Formation of HIV elongation complex in the absence of HIV Tat
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | hydroxyfasudil [Supplementary Concept] | — | 11 |
| 2 | pictilisib | — | 25 |
| 3 | Sorafenib | — | 300 |
| 4 | alsterpaullone | — | 12 |
| 5 | kenpaullone | — | 8 |
| 6 | Tripterygium | — | 300 |
About the Formation of HIV elongation complex in the absence of HIV Tat Pathway
The Formation of HIV elongation complex in the absence of HIV Tat pathway is catalogued in Reactome (ID: R-HSA-167152) and involves 4 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCNT2, CDK7, CDK9, ERCC3.