RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
REACTOME PATHWAYThe RNA Pol II CTD phosphorylation and interaction with CE during HIV infection pathway (Reactome ID: R-HSA-167160) involves 3 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | hydroxyfasudil [Supplementary Concept] | — | 11 |
| 2 | pictilisib | — | 25 |
| 3 | Sorafenib | — | 300 |
| 4 | Levamisole | — | 299 |
| 5 | Tripterygium | — | 300 |
About the RNA Pol II CTD phosphorylation and interaction with CE during HIV infection Pathway
The RNA Pol II CTD phosphorylation and interaction with CE during HIV infection pathway is catalogued in Reactome (ID: R-HSA-167160) and involves 3 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CDK7, ERCC3, RNGTT.