Transcription of the HIV genome
REACTOME PATHWAYThe Transcription of the HIV genome pathway (Reactome ID: R-HSA-167172) involves 5 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Transcription of the HIV genome
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | hydroxyfasudil [Supplementary Concept] | — | 11 |
| 2 | pictilisib | — | 25 |
| 3 | Sorafenib | — | 300 |
| 4 | alsterpaullone | — | 12 |
| 5 | kenpaullone | — | 8 |
| 6 | Levamisole | — | 299 |
| 7 | Tripterygium | — | 300 |
About the Transcription of the HIV genome Pathway
The Transcription of the HIV genome pathway is catalogued in Reactome (ID: R-HSA-167172) and involves 5 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCNT2, CDK7, CDK9, ERCC3, RNGTT.