Telomere Extension By Telomerase
REACTOME PATHWAYThe Telomere Extension By Telomerase pathway (Reactome ID: R-HSA-171319) involves 3 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Telomere Extension By Telomerase
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | alsterpaullone | — | 12 |
| 2 | kenpaullone | — | 8 |
| 3 | sp600125 | — | 117 |
| 4 | Aurintricarboxylic Acid | — | 184 |
| 5 | Methylergonovine | — | 14 |
| 6 | Ethidium | — | 300 |
| 7 | egcg | — | 300 |
| 8 | Oleic Acid | — | 112 |
| 9 | celastrol | — | 300 |
About the Telomere Extension By Telomerase Pathway
The Telomere Extension By Telomerase pathway is catalogued in Reactome (ID: R-HSA-171319) and involves 3 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CCNA1, CDK2, TERT.