Signalling to STAT3
REACTOME PATHWAYThe Signalling to STAT3 pathway (Reactome ID: R-HSA-198745) involves 2 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Signalling to STAT3
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Crizotinib | — | 298 |
| 2 | Sorafenib | — | 300 |
| 3 | Axitinib | — | 298 |
| 4 | pictilisib | — | 25 |
| 5 | sp600125 | — | 117 |
| 6 | Niclosamide | — | 299 |
| 7 | Fingolimod Hydrochloride | — | 56 |
| 8 | Celecoxib | — | 295 |
About the Signalling to STAT3 Pathway
The Signalling to STAT3 pathway is catalogued in Reactome (ID: R-HSA-198745) and involves 2 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include NTRK1, STAT3.