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BiohacksAI

Evidence-Based Biohacking

Patent Pending

Regulation of gene expression in early pancreatic precursor cells

REACTOME PATHWAY
Reactome: R-HSA-2107471 genes22 compounds

The Regulation of gene expression in early pancreatic precursor cells pathway (Reactome ID: R-HSA-210747) involves 1 genes and is affected by 22 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

NR5A2

Compounds Affecting Regulation of gene expression in early pancreatic precursor cells

#CompoundTargets HitStudies
1Anisomycin247
2Azacitidine298
3Azacitidine300
4cycloheximide300
5Digitoxigenin 3 beta,14-Dihydroxy-5 beta-card-20(22)enolide.300
6Digoxigenin 3 beta,12 beta,14-Trihydroxy-5 beta-card-20(22)-enolide.300
7Digoxin299
8Lanatosides Glycosides from DIGITALIS lanata leaf. Lanatoside C has actions similar to DIGOXIN. Mixtures of lanatosides A, B, and C have also been used. (From Martindale,115
9Strophanthidin 3 beta,5,14-Trihydroxy-19-oxo-5 beta-card-20(22)-enolide.300
10Tubercidin300
11tyrphostin 92
12Methylene Blue200
13Progesterone299
14Aldosterone300
15Methotrexate289
16Cilostazol297
17clofilium tosylate4
18dihydrorotenone13
19Ethidium300
20Gemfibrozil297
21Triiodothyronine300
22vinblastine sulfate81

About the Regulation of gene expression in early pancreatic precursor cells Pathway

The Regulation of gene expression in early pancreatic precursor cells pathway is catalogued in Reactome (ID: R-HSA-210747) and involves 1 genes. In the BiohacksAI corpus, 22 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include NR5A2.