The phototransduction cascade
REACTOME PATHWAYThe The phototransduction cascade pathway (Reactome ID: R-HSA-2514856) involves 7 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting The phototransduction cascade
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Gliotoxin | — | 300 |
| 2 | Lovastatin | — | 300 |
| 3 | Axitinib | — | 298 |
| 4 | Crizotinib | — | 298 |
| 5 | Cyclic GMP Guanosine cyclic 3',5'-(hydrogen phosphate). | — | 300 |
| 6 | Dequalinium | — | 136 |
| 7 | Antazoline | — | 229 |
| 8 | Thiabendazole 2-Substituted benzimidazole first introduced in 1962. It is active against | — | 299 |
About the The phototransduction cascade Pathway
The The phototransduction cascade pathway is catalogued in Reactome (ID: R-HSA-2514856) and involves 7 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CHURC1-FNTB, CNGA1, FNTA, FNTB, GRK4.