POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
REACTOME PATHWAYThe POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation pathway (Reactome ID: R-HSA-2892247) involves 2 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Niclosamide | — | 299 |
| 2 | Fingolimod Hydrochloride | — | 56 |
| 3 | Celecoxib | — | 295 |
| 4 | Sorafenib | — | 300 |
| 5 | Crizotinib | — | 298 |
About the POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Pathway
The POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation pathway is catalogued in Reactome (ID: R-HSA-2892247) and involves 2 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include EPHA1, STAT3.