Question 1

What compounds affect the Deactivation of the beta-catenin transactivating complex pathway?

Accepted Answer

22 compounds in the BiohacksAI corpus have documented interactions with genes in the Deactivation of the beta-catenin transactivating complex pathway (Reactome ID: R-HSA-3769402). These compounds target 9 genes within this pathway.

Question 2

What genes are in the Deactivation of the beta-catenin transactivating complex pathway?

Accepted Answer

The Deactivation of the beta-catenin transactivating complex pathway involves 9 genes. Key genes include: ASH2L, CTBP1, DPY30, HDAC1, MEN1, RBBP5, TCF7L2, WDR5, XPO1.

#	Compound	Targets Hit	Studies
1	s adenosylhomocysteine	—	300
2	Vorinostat	—	299
3	trichostatic acid [Supplementary Concept] related to trichostatin	—	300
4	scriptaid	—	53
5	Valproic Acid	—	296
6	pictilisib	—	25
7	Butyric Acid	—	300
8	Ursolic Acid	—	300
9	Celecoxib	—	295
10	Daunorubicin	—	298
11	Bortezomib	—	300
12	Camptothecin	—	300
13	NAD	—	300
14	NAD	—	300
15	NAD	—	300
16	Carmine Coloring matter from	—	300
17	Diiodotyrosine	—	300
18	plumbagin [Supplementary Concept]	—	300
19	oridonin	—	300
20	Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).	—	300
21	Nitroblue Tetrazolium Colorless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases,	—	300
22	pnu74654	—	6

BiohacksAI

Deactivation of the beta-catenin transactivating complex

Genes in this Pathway

Compounds Affecting Deactivation of the beta-catenin transactivating complex

About the Deactivation of the beta-catenin transactivating complex Pathway