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Valproic Acid

A fatty acid with anticonvulsant and anti-manic properties that is used in the treatment of EPILEPSY and BIPOLAR DISORDER. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of VOLTAGE-GATED SODIUM CHANNELS.

296+ PubMed studies analyzed · 7 RCTs · Evidence Score: 43.7

Research Domains

Valproic Acid has been studied across 17 research domains including 🫁 Liver & Detox, ⚡ Energy & Fatigue, 💊 Pain, 🔬 Oncology, 🧠 Focus & Attention. The primary research focus is 🫁 Liver & Detox with 10% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Valproic Acid, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

tubastatin
11 shared targets
nexturastat
11 shared targets
pracinostat
11 shared targets
givinostat
11 shared targets
abexinostat
11 shared targets
azumamide
11 shared targets
dacinostat
11 shared targets
entinostat
11 shared targets
tubacin
11 shared targets
romidepsin
11 shared targets
Loading evidence profile...

This evidence profile for Valproic Acid is generated deterministically from 296 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.