CD28 dependent Vav1 pathway
REACTOME PATHWAYThe CD28 dependent Vav1 pathway pathway (Reactome ID: R-HSA-389359) involves 4 genes and is affected by 16 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting CD28 dependent Vav1 pathway
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Crizotinib | — | 298 |
| 3 | Dasatinib | — | 299 |
| 4 | kenpaullone | — | 8 |
| 5 | Acetic Acid Product of | — | 300 |
| 6 | tyrphostin ag 1478 | — | 4 |
| 7 | Afatinib | — | 297 |
| 8 | Axitinib | — | 298 |
| 9 | piceatannol | — | 300 |
| 10 | sp600125 | — | 117 |
| 11 | Swainsonine | — | 300 |
| 12 | Rosmarinic Acid | — | 300 |
| 13 | Genistein | — | 300 |
| 14 | egcg | — | 300 |
| 15 | casin | — | 10 |
| 16 | Dactinomycin | — | 297 |
About the CD28 dependent Vav1 pathway Pathway
The CD28 dependent Vav1 pathway pathway is catalogued in Reactome (ID: R-HSA-389359) and involves 4 genes. In the BiohacksAI corpus, 16 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CDC42, FYN, GRB2, LCK.