Lysosphingolipid and LPA receptors
REACTOME PATHWAYThe Lysosphingolipid and LPA receptors pathway (Reactome ID: R-HSA-419408) involves 3 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Lysosphingolipid and LPA receptors
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Tripterygium | — | 300 |
| 2 | dihydrorotenone | — | 13 |
| 3 | Ouabain | — | 300 |
| 4 | Flurandrenolone | — | 65 |
| 5 | pirenperone | — | 22 |
| 6 | Camptothecin | — | 300 |
| 7 | Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone | — | 76 |
| 8 | Fingolimod Hydrochloride | — | 56 |
About the Lysosphingolipid and LPA receptors Pathway
The Lysosphingolipid and LPA receptors pathway is catalogued in Reactome (ID: R-HSA-419408) and involves 3 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include S1PR1, S1PR3, S1PR4.