Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
REACTOME PATHWAYThe Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA pathway (Reactome ID: R-HSA-450513) involves 2 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Adenosine Triphosphate | — | 300 |
| 2 | Afatinib | — | 297 |
| 3 | Quercetin | — | 300 |
About the Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Pathway
The Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA pathway is catalogued in Reactome (ID: R-HSA-450513) and involves 2 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include MAPKAPK2, YWHAB.