What genes are in the Organic anion transport by SLC22 transporters pathway?

The Organic anion transport by SLC22 transporters pathway involves 5 genes. Key genes include: SLC22A11, SLC22A12, SLC22A6, SLC22A7, SLC22A8.

Organic anion transport by SLC22 transporters

Q: What compounds affect the Organic anion transport by SLC22 transporters pathway?

36 compounds in the BiohacksAI corpus have documented interactions with genes in the Organic anion transport by SLC22 transporters pathway (Reactome ID: R-HSA-561048). These compounds target 5 genes within this pathway.

REACTOME PATHWAY

Reactome: R-HSA-5610485 genes36 compounds

The Organic anion transport by SLC22 transporters pathway (Reactome ID: R-HSA-561048) involves 5 genes and is affected by 36 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

SLC22A11 SLC22A12 SLC22A6 SLC22A7 SLC22A8

Compounds Affecting Organic anion transport by SLC22 transporters

#	Compound	Targets Hit	Studies
1	Dinoprost	—	252
2	Dinoprostone	—	296
3	Cefamandole Semisynthetic wide-spectrum cephalosporin with prolonged action, probably due to beta-lactamase resistance. It is used also as	—	300
4	Cefazolin	—	300
5	Cefoperazone Semisynthetic broad-spectrum cephalosporin with	—	300
6	cefotaxime	—	299
7	Ceftriaxone	—	299
8	Cephaloridine	—	300
9	Indomethacin	—	297
10	Probenecid	—	298
11	Dicloxacillin	—	297
12	cefadroxil	—	299
13	Thioctic Acid	—	182
14	piperacillin	—	298
15	Oxacillin	—	298
16	Penicillin G	—	298
17	Carnitine	—	300
18	Ampicillin Semi-synthetic derivative of penicillin that functions as	—	294
19	Azlocillin	—	300
20	cefaclor	—	299
21	Cefoxitin	—	300
22	Cloxacillin	—	299
23	Methicillin	—	299
24	Nafcillin	—	297
25	Penicillin V	—	300
26	Tazobactam	—	298
27	p-Aminohippuric Acid	—	300
28	Naproxen	—	1,000
29	Nateglinide	—	295
30	Bumetanide	—	299
31	carbenicillin	—	300
32	Cefmetazole	—	300
33	Furosemide	—	298
34	Glyburide	—	298
35	Dehydroepiandrosterone Sulfate	—	300
36	Sulfinpyrazone	—	300

About the Organic anion transport by SLC22 transporters Pathway

The Organic anion transport by SLC22 transporters pathway is catalogued in Reactome (ID: R-HSA-561048) and involves 5 genes. In the BiohacksAI corpus, 36 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include SLC22A11, SLC22A12, SLC22A6, SLC22A7, SLC22A8.