Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1)
REACTOME PATHWAYThe Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) pathway (Reactome ID: R-HSA-5619043) involves 1 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1)
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Genistein | — | 300 |
| 2 | Resveratrol | — | 298 |
| 3 | Glucose | — | 294 |
| 4 | Kaempferols | — | 300 |
| 5 | Anisomycin | — | 247 |
| 6 | cycloheximide | — | 300 |
| 7 | Emetine | — | 298 |
About the Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) Pathway
The Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1) pathway is catalogued in Reactome (ID: R-HSA-5619043) and involves 1 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include SLC2A1.