PI-3K cascade:FGFR4
REACTOME PATHWAYThe PI-3K cascade:FGFR4 pathway (Reactome ID: R-HSA-5654720) involves 3 genes and is affected by 9 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting PI-3K cascade:FGFR4
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | pictilisib | — | 25 |
| 2 | Wortmannin | — | 300 |
| 3 | ly294002 | — | 11 |
| 4 | alpelisib | — | 227 |
| 5 | Sirolimus | — | 300 |
| 6 | torin 1 | — | 10 |
| 7 | Quercetin | — | 300 |
| 8 | Acrylamide | — | 300 |
| 9 | Dactinomycin | — | 297 |
About the PI-3K cascade:FGFR4 Pathway
The PI-3K cascade:FGFR4 pathway is catalogued in Reactome (ID: R-HSA-5654720) and involves 3 genes. In the BiohacksAI corpus, 9 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include FGFR4, GRB2, PIK3R1.