CD22 mediated BCR regulation
REACTOME PATHWAYThe CD22 mediated BCR regulation pathway (Reactome ID: R-HSA-5690714) involves 2 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting CD22 mediated BCR regulation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Dasatinib | — | 299 |
| 3 | tyrphostin ag 1478 | — | 4 |
| 4 | alsterpaullone | — | 12 |
| 5 | Crizotinib | — | 298 |
| 6 | kenpaullone | — | 8 |
| 7 | sp600125 | — | 117 |
| 8 | celastrol | — | 300 |
About the CD22 mediated BCR regulation Pathway
The CD22 mediated BCR regulation pathway is catalogued in Reactome (ID: R-HSA-5690714) and involves 2 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include LYN, PTPN6.