Question 1

What compounds affect the Protein-protein interactions at synapses pathway?

Accepted Answer

29 compounds in the BiohacksAI corpus have documented interactions with genes in the Protein-protein interactions at synapses pathway (Reactome ID: R-HSA-6794362). These compounds target 13 genes within this pathway.

Question 2

What genes are in the Protein-protein interactions at synapses pathway?

Accepted Answer

The Protein-protein interactions at synapses pathway involves 13 genes. Key genes include: CASK, GRIA1, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRM1, GRM5.

#	Compound	Targets Hit	Studies
1	Glutamic Acid	—	297
2	Glutamic Acid	—	300
3	Ibotenic Acid	—	300
4	Glycine	—	300
5	pentamidine	—	299
6	Dextromethorphan Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of	—	296
7	Dextrorphan Dextro form of levorphanol. It acts as	—	300
8	Levorphanol	—	297
9	cycloserine	—	298
10	Aspartic Acid	—	300
11	D-Aspartic Acid	—	29
12	Ethidium	—	300
13	Dextrothyroxine	—	134
14	Dizocilpine Maleate	—	300
15	Spermine	—	300
16	eliprodil	—	33
17	Memantine AMANTADINE derivative that has some dopaminergic effects. It has been proposed as	—	34
18	alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid	—	300
19	Piracetam	—	300
20	aniracetam	—	110
21	Crizotinib	—	298
22	Kynurenic Acid	—	300
23	Phenformin	—	300
24	Carvedilol	—	296
25	Ibogaine	—	300
26	Sorafenib	—	300
27	sp600125	—	117
28	Ursolic Acid	—	300
29	scutellarein	—	113

BiohacksAI

Protein-protein interactions at synapses

Genes in this Pathway

Compounds Affecting Protein-protein interactions at synapses

About the Protein-protein interactions at synapses Pathway