FGFR2 alternative splicing
REACTOME PATHWAYThe FGFR2 alternative splicing pathway (Reactome ID: R-HSA-6803529) involves 2 genes and is affected by 13 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting FGFR2 alternative splicing
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Azauridine | — | 300 |
| 2 | Carboxin | — | 174 |
| 3 | Digitoxin | — | 300 |
| 4 | Digoxin | — | 299 |
| 5 | Ethylenethiourea | — | 300 |
| 6 | Nadolol | — | 297 |
| 7 | Ouabain | — | 300 |
| 8 | streptonigrin | — | 299 |
| 9 | Sulfadiazine | — | 298 |
| 10 | Thioridazine | — | 35 |
| 11 | triflupromazine hydrochloride | — | 12 |
| 12 | Camptothecin | — | 300 |
| 13 | Quercetin | — | 300 |
About the FGFR2 alternative splicing Pathway
The FGFR2 alternative splicing pathway is catalogued in Reactome (ID: R-HSA-6803529) and involves 2 genes. In the BiohacksAI corpus, 13 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HNRNPA1, PTBP1.