mRNA Splicing - Major Pathway
REACTOME PATHWAYThe mRNA Splicing - Major Pathway pathway (Reactome ID: R-HSA-72163) involves 4 genes and is affected by 17 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting mRNA Splicing - Major Pathway
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Azauridine | — | 300 |
| 2 | Carboxin | — | 174 |
| 3 | Digitoxin | — | 300 |
| 4 | Digoxin | — | 299 |
| 5 | Ethylenethiourea | — | 300 |
| 6 | Nadolol | — | 297 |
| 7 | Ouabain | — | 300 |
| 8 | streptonigrin | — | 299 |
| 9 | Sulfadiazine | — | 298 |
| 10 | Thioridazine | — | 35 |
| 11 | triflupromazine hydrochloride | — | 12 |
| 12 | Adenosine Diphosphate Adenosine 5'-(trihydrogen diphosphate). | — | 300 |
| 13 | Hexachlorophene | — | 300 |
| 14 | Ergosterol | — | 300 |
| 15 | Camptothecin | — | 300 |
| 16 | Quercetin | — | 300 |
| 17 | trichostatic acid [Supplementary Concept] related to trichostatin | — | 300 |
About the mRNA Splicing - Major Pathway Pathway
The mRNA Splicing - Major Pathway pathway is catalogued in Reactome (ID: R-HSA-72163) and involves 4 genes. In the BiohacksAI corpus, 17 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HNRNPA1, HSPA8, PTBP1, SF3B3.