RUNX1 regulates transcription of genes involved in BCR signaling
REACTOME PATHWAYThe RUNX1 regulates transcription of genes involved in BCR signaling pathway (Reactome ID: R-HSA-8939245) involves 3 genes and is affected by 16 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RUNX1 regulates transcription of genes involved in BCR signaling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Aurintricarboxylic Acid | — | 184 |
| 2 | Dihydroxyphenylalanine | — | 300 |
| 3 | Disulfiram | — | 297 |
| 4 | Ethidium | — | 300 |
| 5 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 6 | Daunorubicin | — | 298 |
| 7 | Fusaric Acid | — | 300 |
| 8 | Harmaline | — | 300 |
| 9 | Dasatinib | — | 299 |
| 10 | Afatinib | — | 297 |
| 11 | alsterpaullone | — | 12 |
| 12 | Axitinib | — | 298 |
| 13 | Crizotinib | — | 298 |
| 14 | Sorafenib | — | 300 |
| 15 | sp600125 | — | 117 |
| 16 | tyrphostin ag 1478 | — | 4 |
About the RUNX1 regulates transcription of genes involved in BCR signaling Pathway
The RUNX1 regulates transcription of genes involved in BCR signaling pathway is catalogued in Reactome (ID: R-HSA-8939245) and involves 3 genes. In the BiohacksAI corpus, 16 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include BLK, CBFB, RUNX1.