RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
REACTOME PATHWAYThe RUNX1 regulates transcription of genes involved in differentiation of myeloid cells pathway (Reactome ID: R-HSA-8939246) involves 3 genes and is affected by 12 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting RUNX1 regulates transcription of genes involved in differentiation of myeloid cells
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Aurintricarboxylic Acid | — | 184 |
| 2 | Dihydroxyphenylalanine | — | 300 |
| 3 | Disulfiram | — | 297 |
| 4 | Ethidium | — | 300 |
| 5 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 6 | Daunorubicin | — | 298 |
| 7 | Fusaric Acid | — | 300 |
| 8 | Harmaline | — | 300 |
| 9 | Papaverine | — | 299 |
| 10 | Colchicine | — | 300 |
| 11 | Etazolate | — | 66 |
| 12 | Nocodazole Nocodazole is | — | 215 |
About the RUNX1 regulates transcription of genes involved in differentiation of myeloid cells Pathway
The RUNX1 regulates transcription of genes involved in differentiation of myeloid cells pathway is catalogued in Reactome (ID: R-HSA-8939246) and involves 3 genes. In the BiohacksAI corpus, 12 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CBFB, CREBBP, RUNX1.