Plasma lipoprotein assembly
REACTOME PATHWAYThe Plasma lipoprotein assembly pathway (Reactome ID: R-HSA-8963898) involves 4 genes and is affected by 5 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Plasma lipoprotein assembly
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | hydroxyfasudil [Supplementary Concept] | — | 11 |
| 2 | alpelisib | — | 227 |
| 3 | juglone hydroxylase [Supplementary Concept] catalyzes | — | 279 |
| 4 | Equilin | — | 216 |
| 5 | Sphingosine | — | 300 |
About the Plasma lipoprotein assembly Pathway
The Plasma lipoprotein assembly pathway is catalogued in Reactome (ID: R-HSA-8963898) and involves 4 genes. In the BiohacksAI corpus, 5 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include P4HB, PRKACA, PRKACB, PRKACG.