HDL remodeling
REACTOME PATHWAYThe HDL remodeling pathway (Reactome ID: R-HSA-8964058) involves 1 genes and is affected by 11 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting HDL remodeling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Warfarin | — | 1,000 |
| 2 | Mycophenolic Acid Compound derived from Penicillium stoloniferum and related species. It blocks de novo biosynthesis of purine nucleotides by inhibition of | — | 300 |
| 3 | Tolbutamide | — | 300 |
| 4 | cbd | — | 298 |
| 5 | egcg | — | 300 |
| 6 | cannabidiol | — | 296 |
| 7 | Catechin | — | 300 |
| 8 | Evans Blue | — | 300 |
| 9 | Olmesartan Medoxomil | — | 300 |
| 10 | Phenylbutazone | — | 300 |
| 11 | Trazodone | — | 297 |
About the HDL remodeling Pathway
The HDL remodeling pathway is catalogued in Reactome (ID: R-HSA-8964058) and involves 1 genes. In the BiohacksAI corpus, 11 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ALB.