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Tolbutamide

A sulphonylurea hypoglycemic agent with actions and uses similar to those of CHLORPROPAMIDE. (From Martindale, The Extra Pharmacopoeia, 30th ed, p290)

300+ PubMed studies analyzed · 13 RCTs · Evidence Score: 45.6

Research Domains

Tolbutamide has been studied across 16 research domains including 🔥 Metabolic, 🧬 Hormones, 🫁 Liver & Detox, 🧠 Focus & Attention, 🦴 Bone & Joint. The primary research focus is 🔥 Metabolic with 51% of studies addressing this area.

Similar Compounds by Shared Targets

The following compounds share molecular targets with Tolbutamide, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.

Nicorandil
4 shared targets
Aztreonam
3 shared targets
Cromakalim
2 shared targets
Pinacidil
3 shared targets
Midodrine
3 shared targets
Carbimazole
3 shared targets
Metaraminol
3 shared targets
Modafinil
3 shared targets
Sulfadoxine
3 shared targets
Felbamate
3 shared targets
Loading evidence profile...

This evidence profile for Tolbutamide is generated deterministically from 300 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.

Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.