A serotonin uptake inhibitor that is used as an antidepressive agent. It has been shown to be effective in patients with major depressive disorders and other subsets of depressive disorders. It is generally more useful in depressive disorders associated with insomnia and anxiety. This drug does not aggravate psychotic symptoms in patients with schizophrenia or schizoaffective disorders. (From AMA Drug Evaluations Annual, 1994, p309)
Trazodone has been studied across 19 research domains including 🌤️ Mood & Depression, 😴 Sleep, 🧘 Stress & Anxiety, 🧠 Neuroprotection, 🧠 Focus & Attention. The primary research focus is 🌤️ Mood & Depression with 40% of studies addressing this area.
The following compounds share molecular targets with Trazodone, based on binding affinity data from BindingDB and ChEMBL. Sorted by shared target overlap.
This evidence profile for Trazodone is generated deterministically from 297 PubMed-indexed studies. All data is corpus-verified with Merkle proofs. BiohacksAI does not provide medical advice. Always consult a healthcare professional before starting any supplement regimen.
Data source: PubMed/MEDLINE (NLM). Corpus version: current. Patent pending (EVE-PAT-2026-001). © 2026 Organiq Sweden AB.