Interleukin-9 signaling
REACTOME PATHWAYThe Interleukin-9 signaling pathway (Reactome ID: R-HSA-8985947) involves 4 genes and is affected by 14 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Interleukin-9 signaling
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Sorafenib | — | 300 |
| 2 | Budesonide | — | 1,000 |
| 3 | Methylene Blue | — | 200 |
| 4 | egcg | — | 300 |
| 5 | Flurandrenolone | — | 65 |
| 6 | Hexachlorophene | — | 300 |
| 7 | streptonigrin | — | 299 |
| 8 | Methotrexate | — | 289 |
| 9 | Crizotinib | — | 298 |
| 10 | sp600125 | — | 117 |
| 11 | Axitinib | — | 298 |
| 12 | Niclosamide | — | 299 |
| 13 | Fingolimod Hydrochloride | — | 56 |
| 14 | Celecoxib | — | 295 |
About the Interleukin-9 signaling Pathway
The Interleukin-9 signaling pathway is catalogued in Reactome (ID: R-HSA-8985947) and involves 4 genes. In the BiohacksAI corpus, 14 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include JAK3, STAT1, STAT3, STAT5A.