TICAM1-dependent activation of IRF3/IRF7
REACTOME PATHWAYThe TICAM1-dependent activation of IRF3/IRF7 pathway (Reactome ID: R-HSA-9013973) involves 3 genes and is affected by 11 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting TICAM1-dependent activation of IRF3/IRF7
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | amlexanox | — | 96 |
| 2 | Crizotinib | — | 298 |
| 3 | Budesonide | — | 1,000 |
| 4 | Dibucaine | — | 299 |
| 5 | Dimethylphenylpiperazinium Iodide | — | 33 |
| 6 | Edaravone | — | 298 |
| 7 | Fluocinolone Acetonide | — | 295 |
| 8 | Podophyllotoxin | — | 14 |
| 9 | Sulfadimethoxine | — | 300 |
| 10 | vinblastine sulfate | — | 81 |
| 11 | Axitinib | — | 298 |
About the TICAM1-dependent activation of IRF3/IRF7 Pathway
The TICAM1-dependent activation of IRF3/IRF7 pathway is catalogued in Reactome (ID: R-HSA-9013973) and involves 3 genes. In the BiohacksAI corpus, 11 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include IKBKE, TBK1, TLR3.