Loss of MECP2 binding ability to the NCoR/SMRT complex
REACTOME PATHWAYThe Loss of MECP2 binding ability to the NCoR/SMRT complex pathway (Reactome ID: R-HSA-9022537) involves 3 genes and is affected by 12 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Loss of MECP2 binding ability to the NCoR/SMRT complex
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Vorinostat | — | 299 |
| 2 | trichostatic acid [Supplementary Concept] related to trichostatin | — | 300 |
| 3 | scriptaid | — | 53 |
| 4 | Butyric Acid | — | 300 |
| 5 | pictilisib | — | 25 |
| 6 | Valproic Acid | — | 296 |
| 7 | Ursolic Acid | — | 300 |
| 8 | Bortezomib | — | 300 |
| 9 | Camptothecin | — | 300 |
| 10 | Celecoxib | — | 295 |
| 11 | Daunorubicin | — | 298 |
| 12 | Biotin | — | 297 |
About the Loss of MECP2 binding ability to the NCoR/SMRT complex Pathway
The Loss of MECP2 binding ability to the NCoR/SMRT complex pathway is catalogued in Reactome (ID: R-HSA-9022537) and involves 3 genes. In the BiohacksAI corpus, 12 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include HDAC3, NCOR1, NCOR2.