Regulation of localization of FOXO transcription factors
REACTOME PATHWAYThe Regulation of localization of FOXO transcription factors pathway (Reactome ID: R-HSA-9614399) involves 4 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Regulation of localization of FOXO transcription factors
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Resveratrol | — | 298 |
| 2 | ly294002 | — | 11 |
| 3 | Idarubicin | — | 299 |
| 4 | Masoprocol | — | 300 |
| 5 | Quercetin | — | 300 |
| 6 | hydroxyfasudil [Supplementary Concept] | — | 11 |
About the Regulation of localization of FOXO transcription factors Pathway
The Regulation of localization of FOXO transcription factors pathway is catalogued in Reactome (ID: R-HSA-9614399) and involves 4 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AKT3, FOXO3, YWHAB, YWHAG.