CD163 mediating an anti-inflammatory response
REACTOME PATHWAYThe CD163 mediating an anti-inflammatory response pathway (Reactome ID: R-HSA-9662834) involves 5 genes and is affected by 18 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting CD163 mediating an anti-inflammatory response
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Prednisolone | — | 1,000 |
| 2 | Sorafenib | — | 300 |
| 3 | Dasatinib | — | 299 |
| 4 | Afatinib | — | 297 |
| 5 | egcg | — | 300 |
| 6 | fisetin | — | 78 |
| 7 | myricetin-3-O-galactopyranoside [Supplementary Concept] | — | 300 |
| 8 | Quercetin | — | 300 |
| 9 | Anisomycin | — | 247 |
| 10 | Celecoxib | — | 295 |
| 11 | isorhamnetin-3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-6)-beta-D-galactopyranoside [Supplementary Concept] from | — | 300 |
| 12 | tyrphostin ag 1478 | — | 4 |
| 13 | withaferin | — | 300 |
| 14 | Bisphenol A-Glycidyl Methacrylate | — | 197 |
| 15 | Kaempferols | — | 300 |
| 16 | Diminazene | — | 300 |
| 17 | silver sulfadiazine | — | 299 |
| 18 | Wortmannin | — | 300 |
About the CD163 mediating an anti-inflammatory response Pathway
The CD163 mediating an anti-inflammatory response pathway is catalogued in Reactome (ID: R-HSA-9662834) and involves 5 genes. In the BiohacksAI corpus, 18 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include ADAM17, FURIN, IL6, MAPK14, PLK2.