SARS-CoV-2 targets host intracellular signalling and regulatory pathways
REACTOME PATHWAYThe SARS-CoV-2 targets host intracellular signalling and regulatory pathways pathway (Reactome ID: R-HSA-9755779) involves 4 genes and is affected by 7 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting SARS-CoV-2 targets host intracellular signalling and regulatory pathways
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | sp600125 | — | 117 |
| 2 | alsterpaullone | — | 12 |
| 3 | kenpaullone | — | 8 |
| 4 | Idarubicin | — | 299 |
| 5 | Masoprocol | — | 300 |
| 6 | Quercetin | — | 300 |
| 7 | hydroxyfasudil [Supplementary Concept] | — | 11 |
About the SARS-CoV-2 targets host intracellular signalling and regulatory pathways Pathway
The SARS-CoV-2 targets host intracellular signalling and regulatory pathways pathway is catalogued in Reactome (ID: R-HSA-9755779) and involves 4 genes. In the BiohacksAI corpus, 7 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include AKT3, PDPK1, YWHAB, YWHAG.