What compounds affect the Maturation of hRSV A proteins pathway?

36 compounds in the BiohacksAI corpus have documented interactions with genes in the Maturation of hRSV A proteins pathway (Reactome ID: R-HSA-9828806). These compounds target 8 genes within this pathway.

What genes are in the Maturation of hRSV A proteins pathway?

The Maturation of hRSV A proteins pathway involves 8 genes. Key genes include: CSNK2A1, CSNK2A2, CSNK2B, FURIN, KPNB1, PPP1CA, PPP1CC, XPO1.

Maturation of hRSV A proteins

REACTOME PATHWAY

Reactome: R-HSA-98288068 genes36 compounds

The Maturation of hRSV A proteins pathway (Reactome ID: R-HSA-9828806) involves 8 genes and is affected by 36 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.

Genes in this Pathway

CSNK2A1 CSNK2A2 CSNK2B FURIN KPNB1 PPP1CA PPP1CC XPO1

Compounds Affecting Maturation of hRSV A proteins

#	Compound	Targets Hit	Studies
1	Apigenin 5,7,4'-trihydroxy-flavone,	—	300
2	Emodin Purgative anthraquinone found in several plants, especially RHAMNUS PURSHIANA. It was formerly used as	—	300
3	Quercetin	—	300
4	fisetin	—	78
5	Kaempferols	—	300
6	Luteolin 5,7,3',4'-tetrahydroxy-flavone,	—	150
7	myricetin-3-O-galactopyranoside [Supplementary Concept]	—	300
8	chrysin	—	300
9	Vanillic Acid	—	300
10	ly294002	—	11
11	Chlorhexidine	—	299
12	Dichlororibofuranosylbenzimidazole	—	26
13	Adenylyl Imidodiphosphate 5'-Adenylic acid, monoanhydride with imidodiphosphoric acid.	—	300
14	alsterpaullone	—	12
15	kenpaullone	—	8
16	sp600125	—	117
17	Anthralin	—	299
18	Hexachlorophene	—	300
19	Mometasone Furoate	—	292
20	Oxytetracycline	—	300
21	Thyroxine	—	994
22	Tannins Polyphenolic compounds with molecular weights of around 500-3000 daltons and containing enough hydroxyl groups (1-2 per 100 MW) for effective cross linking of other compounds (ASTRINGENTS).	—	300
23	Aurintricarboxylic Acid	—	184
24	Calcimycin	—	216
25	Clotrimazole	—	296
26	Fluspirilene	—	74
27	Tetracycline	—	300
28	Thyroxine	—	300
29	pictilisib	—	25
30	Axitinib	—	298
31	plumbagin [Supplementary Concept]	—	300
32	oridonin	—	300
33	Reserpine	—	297
34	Diminazene	—	300
35	silver sulfadiazine	—	299
36	Okadaic Acid	—	300

About the Maturation of hRSV A proteins Pathway

The Maturation of hRSV A proteins pathway is catalogued in Reactome (ID: R-HSA-9828806) and involves 8 genes. In the BiohacksAI corpus, 36 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include CSNK2A1, CSNK2A2, CSNK2B, FURIN, KPNB1.