TGFBR3 PTM regulation
REACTOME PATHWAYThe TGFBR3 PTM regulation pathway (Reactome ID: R-HSA-9839383) involves 7 genes and is affected by 6 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting TGFBR3 PTM regulation
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Dihydroergocristine | — | 187 |
| 2 | Resveratrol | — | 298 |
| 3 | Astemizole Antihistamine drug now withdrawn from | — | 280 |
| 4 | Leflunomide | — | 297 |
| 5 | Propafenone | — | 14 |
| 6 | Thioridazine | — | 35 |
About the TGFBR3 PTM regulation Pathway
The TGFBR3 PTM regulation pathway is catalogued in Reactome (ID: R-HSA-9839383) and involves 7 genes. In the BiohacksAI corpus, 6 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include APH1A, APH1B, MMP14, NCSTN, PSEN1.