Co-inhibition by BTLA
REACTOME PATHWAYThe Co-inhibition by BTLA pathway (Reactome ID: R-HSA-9927353) involves 2 genes and is affected by 3 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting Co-inhibition by BTLA
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | celastrol | — | 300 |
| 2 | Sorafenib | — | 300 |
| 3 | Dactinomycin | — | 297 |
About the Co-inhibition by BTLA Pathway
The Co-inhibition by BTLA pathway is catalogued in Reactome (ID: R-HSA-9927353) and involves 2 genes. In the BiohacksAI corpus, 3 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include GRB2, PTPN6.