ATP-dependent chromatin remodelers
REACTOME PATHWAYThe ATP-dependent chromatin remodelers pathway (Reactome ID: R-HSA-9932444) involves 2 genes and is affected by 8 compounds in the BiohacksAI evidence corpus. Compound-pathway associations are derived from target overlap: a compound is linked to this pathway if it targets ≥2 genes within the pathway.
Genes in this Pathway
Compounds Affecting ATP-dependent chromatin remodelers
| # | Compound | Targets Hit | Studies |
|---|---|---|---|
| 1 | Genistein | — | 300 |
| 2 | alsterpaullone | — | 12 |
| 3 | calycosin | — | 300 |
| 4 | kenpaullone | — | 8 |
| 5 | chrysin | — | 300 |
| 6 | Disulfiram | — | 297 |
| 7 | Lovastatin | — | 300 |
| 8 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | — | 150 |
About the ATP-dependent chromatin remodelers Pathway
The ATP-dependent chromatin remodelers pathway is catalogued in Reactome (ID: R-HSA-9932444) and involves 2 genes. In the BiohacksAI corpus, 8 compounds have documented interactions with at least 2 genes in this pathway, establishing mechanistic relevance. Key pathway genes include PBRM1, SMARCA2.