ABL1
MOLECULAR TARGETABL proto-oncogene 1, non-receptor tyrosine kinase
ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) is targeted by 21 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ABL1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | Sorafenib | 3.95 | 51 |
| 2 | Axitinib | 3.66 | 38 |
| 3 | Dasatinib | 3.47 | 31 |
| 4 | Crizotinib | 3.04 | 20 |
| 5 | Afatinib | 2.77 | 15 |
| 6 | Avapritinib | 1.39 | 3 |
| 7 | Biotin | 1.39 | 3 |
| 8 | 19-((1'S,4'R)-4'-hydroxy-1'-methoxy-2'-oxopentyl)geldanamycin [Supplementary Concept] | 1.39 | 3 |
| 9 | Imatinib Mesylate | 1.39 | 3 |
| 10 | triolimus [Supplementary Concept] | 1.39 | 3 |
| 11 | tyrphostin ag 1478 | 1.10 | 2 |
| 12 | Genistein | 0.69 | 1 |
| 13 | myricetin-3-O-galactopyranoside [Supplementary Concept] | 0.69 | 1 |
| 14 | pterostilbene | 0.69 | 1 |
| 15 | Quercetin | 0.69 | 1 |
| 16 | Adenosine Triphosphate | 0.69 | 1 |
| 17 | alpelisib | 0.69 | 1 |
| 18 | alsterpaullone | 0.69 | 1 |
| 19 | kenpaullone | 0.69 | 1 |
| 20 | Nocodazole Nocodazole is | 0.69 | 1 |
| 21 | Oxytetracycline | 0.69 | 1 |
About ABL1 as a Drug Target
ABL1 (ABL proto-oncogene 1, non-receptor tyrosine kinase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 21 compounds with documented ABL1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ABL1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.