What compounds target ACES?

BiohacksAI has identified 34 compounds that interact with ACES (Acetylcholinesterase). Top compounds include: bdb huperzine a 13e 1 amino 13 ethylidene 11 methyl 6 azatricyclo 7 3 1 0 2 7 tridec, bdb 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14 hexaen 3 , bdb 7 fluoro 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14 , bdb hupriney hydrochloride huprine y hcl chembl536047, bdb rac 5 fluoro 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ACES (Acetylcholinesterase)?

ACES is Acetylcholinesterase. It is a molecular target for 34 compounds documented in PubMed bioassay data.

ACES

MOLECULAR TARGET

Acetylcholinesterase

34 compounds

ACES (Acetylcholinesterase) is targeted by 34 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ACES

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	bdb huperzine a 13e 1 amino 13 ethylidene 11 methyl 6 azatricyclo 7 3 1 0 2 7 tridec	1.61	4
2	bdb 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14 hexaen 3	1.39	3
3	bdb 7 fluoro 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14	1.10	2
4	bdb hupriney hydrochloride huprine y hcl chembl536047	1.10	2
5	bdb rac 5 fluoro 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9	1.10	2
6	bdb chembl4566976	0.69	1
7	bdb 11 amino 8 methyl 5 6 9 10 tetrahydro 6 10 methanocyclooctabenzo b 1 8 naphthyri	0.69	1
8	bdb 15 ethyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14 hexaen 3 a	0.69	1
9	bdb 15 ethyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 15 hexaen 3 a	0.69	1
10	bdb 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 15 hexaen 3	0.69	1
11	bdb 7 chloro 15 methyl 10 azatetracyclo 11 3 1 0 2 11 0 4 9 heptadeca 2 4 9 5 7 10 1	0.69	1
12	bdb 9e 7 7 1 2 3 4 tetrahydroacridin 9 ylamino heptylamino 9 ethylidene 3 methylbicy	0.69	1
13	bdb 9e n1 7 1 2 3 4 tetrahydroacridin 9 ylamino heptyl 9 ethylidene 7 methylbicyclo	0.69	1
14	bdb chembl4072478	0.69	1
15	bdb chembl4438626	0.69	1
16	bdb chembl4462369	0.69	1
17	bdb chembl4469066	0.69	1
18	bdb chembl4469343	0.69	1
19	bdb chembl4471659	0.69	1
20	bdb chembl4558495	0.69	1
21	bdb chembl4591167	0.69	1
22	bdb chembl4741162	0.69	1
23	bdb chembl4743210	0.69	1
24	bdb chembl4744528	0.69	1
25	bdb chembl4748114	0.69	1
26	bdb chembl4754487	0.69	1
27	bdb chembl4782267	0.69	1
28	bdb chembl4782921	0.69	1
29	bdb chembl4788434	0.69	1
30	bdb chembl4794769	0.69	1
31	bdb n 2 azidoethyl 3 chloro 6 7 10 11 tetrahydro 12 ylamino 9 ethyl 7 11 methanocycl	0.69	1
32	bdb n 2 azidoethyl 3 chloro 6 7 10 11 tetrahydro 12 ylamino 9 methyl 7 11 methanocyc	0.69	1
33	bdb n 2 hydroxyethyl 3 chloro 6 7 10 11 tetrahydro 12 ylamino 9 ethyl 7 11 methanocy	0.69	1
34	bdb n 3 amino 7 chloro 15 methyl 10 azatetracyclo 11 3 1 0 2 11 0 4 9 heptadeca 2 4	0.69	1

About ACES as a Drug Target

ACES (Acetylcholinesterase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 34 compounds with documented ACES interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ACES inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.