ACHA3
MOLECULAR TARGETNeuronal acetylcholine receptor subunit alpha-3
ACHA3 (Neuronal acetylcholine receptor subunit alpha-3) is targeted by 25 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting ACHA3
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | bdb 6 6 chloro pyridin 3 yl 8 aza bicyclo 3 2 1 octan 3 ol chembl421553 | 0.69 | 1 |
| 2 | bdb chembl2057712 | 0.69 | 1 |
| 3 | bdb chembl2057714 | 0.69 | 1 |
| 4 | bdb chembl298826 epibatidine 2 6 chloro pyridin 3 yl 7 aza bicyclo 2 2 1 heptane epi | 0.69 | 1 |
| 5 | bdb chembl3094062 | 0.69 | 1 |
| 6 | bdb chembl3094063 | 0.69 | 1 |
| 7 | bdb chembl4437189 | 0.69 | 1 |
| 8 | bdb chembl4437323 | 0.69 | 1 |
| 9 | bdb chembl4438684 | 0.69 | 1 |
| 10 | bdb chembl4440403 | 0.69 | 1 |
| 11 | bdb chembl4442125 | 0.69 | 1 |
| 12 | bdb chembl4443082 | 0.69 | 1 |
| 13 | bdb chembl4450133 | 0.69 | 1 |
| 14 | bdb chembl4453215 | 0.69 | 1 |
| 15 | bdb chembl4453542 | 0.69 | 1 |
| 16 | bdb chembl4463888 | 0.69 | 1 |
| 17 | bdb chembl4468230 | 0.69 | 1 |
| 18 | bdb chembl4468804 | 0.69 | 1 |
| 19 | bdb chembl4472617 | 0.69 | 1 |
| 20 | bdb chembl4474896 | 0.69 | 1 |
| 21 | bdb chembl4521227 | 0.69 | 1 |
| 22 | bdb chembl4535466 | 0.69 | 1 |
| 23 | bdb chembl4557590 | 0.69 | 1 |
| 24 | bdb chembl4559236 | 0.69 | 1 |
| 25 | bdb 18 methoxycoronaridine | 0.69 | 1 |
About ACHA3 as a Drug Target
ACHA3 (Neuronal acetylcholine receptor subunit alpha-3) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 25 compounds with documented ACHA3 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
ACHA3 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.