What compounds target ACHA7?

BiohacksAI has identified 46 compounds that interact with ACHA7 (Neuronal acetylcholine receptor subunit alpha-7). Top compounds include: bdb chembl1258006, bdb chembl1258005, bdb benzo b thiophene 2 carboxylic acid 1 aza bicyclo 2 2 2 oct 3 yl amide chembl365, bdb chembl1257896, bdb chembl2057712. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ACHA7 (Neuronal acetylcholine receptor)?

ACHA7 is Neuronal acetylcholine receptor subunit alpha-7. It is a molecular target for 46 compounds documented in PubMed bioassay data.

ACHA7

MOLECULAR TARGET

Neuronal acetylcholine receptor subunit alpha-7

46 compounds

ACHA7 (Neuronal acetylcholine receptor subunit alpha-7) is targeted by 46 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ACHA7

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	bdb chembl1258006	1.39	3
2	bdb chembl1258005	1.39	3
3	bdb benzo b thiophene 2 carboxylic acid 1 aza bicyclo 2 2 2 oct 3 yl amide chembl365	1.10	2
4	bdb chembl1257896	1.10	2
5	bdb chembl2057712	0.69	1
6	bdb chembl2057714	0.69	1
7	bdb chembl298826 epibatidine 2 6 chloro pyridin 3 yl 7 aza bicyclo 2 2 1 heptane epi	0.69	1
8	bdb chembl3094062	0.69	1
9	bdb chembl3094063	0.69	1
10	bdb chembl4437189	0.69	1
11	bdb chembl4437323	0.69	1
12	bdb chembl4438684	0.69	1
13	bdb chembl4440403	0.69	1
14	bdb chembl4442125	0.69	1
15	bdb chembl4443082	0.69	1
16	bdb chembl4450133	0.69	1
17	bdb chembl4453215	0.69	1
18	bdb chembl4453542	0.69	1
19	bdb chembl4463888	0.69	1
20	bdb chembl4468230	0.69	1
21	bdb chembl4468804	0.69	1
22	bdb chembl4472617	0.69	1
23	bdb chembl4474896	0.69	1
24	bdb chembl4521227	0.69	1
25	bdb chembl4535466	0.69	1
26	bdb chembl4557590	0.69	1
27	bdb chembl4559236	0.69	1
28	bdb 2 2 bithiophenyl 5 carboxylic acid 1 aza bicyclo 2 2 2 oct 3 yl amide chembl1951	0.69	1
29	bdb 5 n 3 pyridylmethyl 2 r spiro 4 azabicyclo 2 2 2 octane 2 2 furo 2 3 b pyridine	0.69	1
30	bdb 5 phenyl 2 r spiro 4 azabicyclo 2 2 2 octane 2 2 furo 2 3 b pyridine chembl19534	0.69	1
31	bdb 5 phenyl thiophene 2 carboxylic acid 1 aza bicyclo 2 2 2 oct 3 yl amide chembl19	0.69	1
32	bdb azidoepibatidine 2 5 azido 6 chloro pyridin 3 yl 7 aza bicyclo 2 2 1 heptane che	0.69	1
33	bdb chembl2177523	0.69	1
34	bdb chembl2177525	0.69	1
35	bdb chembl2177527	0.69	1
36	bdb chembl2177534	0.69	1
37	bdb chembl2177542	0.69	1
38	bdb chembl2177544	0.69	1
39	bdb chembl2177546	0.69	1
40	bdb chembl2177548	0.69	1
41	bdb chembl2177550	0.69	1
42	bdb chembl2177554	0.69	1
43	bdb chembl2178154	0.69	1
44	bdb chembl4084621	0.69	1
45	bdb n 3r 1 azabicyclo 2 2 2 oct 3 yl 5 phenylthiophene 2 carboxamide chembl195329	0.69	1
46	bdb n 3s 1 azabicyclo 2 2 2 oct 3 yl 5 phenylthiophene 2 carboxamide acetate chembl1	0.69	1

About ACHA7 as a Drug Target

ACHA7 (Neuronal acetylcholine receptor subunit alpha-7) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 46 compounds with documented ACHA7 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ACHA7 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.