What compounds target ACM2?

BiohacksAI has identified 96 compounds that interact with ACM2 (Muscarinic acetylcholine receptor M2). Top compounds include: bdb atropen atropine, bdb chembl116590 cas 132 17 2 nsc 2344 benztropine, bdb mequitazine 3 10h phenothiazin 10 ylmethyl 1 azabicyclo 2 2 2 octan 1 ium zinc01, bdb chembl516641 hyperforin, bdb chembl2205836. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ACM2 (Muscarinic acetylcholine receptor)?

ACM2 is Muscarinic acetylcholine receptor M2. It is a molecular target for 96 compounds documented in PubMed bioassay data.

ACM2

MOLECULAR TARGET

Muscarinic acetylcholine receptor M2

96 compounds

ACM2 (Muscarinic acetylcholine receptor M2) is targeted by 96 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ACM2

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	bdb atropen atropine	1.79	5
2	bdb chembl116590 cas 132 17 2 nsc 2344 benztropine	1.39	3
3	bdb mequitazine 3 10h phenothiazin 10 ylmethyl 1 azabicyclo 2 2 2 octan 1 ium zinc01	1.10	2
4	bdb chembl516641 hyperforin	0.69	1
5	bdb chembl2205836	0.69	1
6	bdb chembl2205811	0.69	1
7	bdb n 2 3 fluorophenyl ethyl 8 aminopentacyclo 5 4 0 02 6 03 10 05 9 undecane chembl	0.69	1
8	bdb chembl2205812	0.69	1
9	bdb chembl2205813	0.69	1
10	bdb chembl2205823	0.69	1
11	bdb chembl2205825	0.69	1
12	bdb chembl1189234 chembl538300 11 benzyl 11 azahexacyclo 5 4 1 02 6 03 10 04 8 09 12	0.69	1
13	bdb chembl2205816	0.69	1
14	bdb 3 hydroxy 2 phenyl propionic acid 9 methyl 3 oxa 9 aza tricyclo 3 3 1 0 2 4 non	0.69	1
15	bdb 4 hydroxy 1 aza bicyclo 3 3 1 non 3 ene 3 carboxylic acid ethyl ester chembl3064	0.69	1
16	bdb djocicqnbmtmng	0.69	1
17	bdb exo 8 benzyloxymethyl 4 hydroxy 1 aza bicyclo 3 3 1 non 3 ene 3 carboxylic acid	0.69	1
18	bdb iczvktvmhvhoqi	0.69	1
19	bdb isoptpo hyoscine scopolamine	0.69	1
20	bdb 4 nitro benzoic acid 8 aza bicyclo 3 2 1 oct 6 yl ester chembl315428	0.69	1
21	bdb benzoic acid 8 aza bicyclo 3 2 1 oct 6 yl ester chembl84113	0.69	1
22	bdb cyclohexanecarboxylic acid 8 aza bicyclo 3 2 1 oct 6 yl ester chembl82754	0.69	1
23	bdb propionic acid 8 methyl 8 aza bicyclo 3 2 1 oct 6 yl ester chembl440138	0.69	1
24	bdb 3 2 adamantan 1 yl ethylamino methyl 3 4 dihydro 2h benzo b 1 4 dioxepin 3 yl di	0.69	1
25	bdb 3 2 bromo benzyl phenyl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1 octane	0.69	1
26	bdb 3 3 bromo benzyl phenyl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1 octane	0.69	1
27	bdb 3 3 cyano benzyl thiophen 3 yl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1	0.69	1
28	bdb 3 4 bromo benzyl phenyl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1 octane	0.69	1
29	bdb 3 4 cyano benzyl phenyl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1 octane	0.69	1
30	bdb 3 benzyl phenyl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1 octane bromide	0.69	1
31	bdb 3 benzyl thiophen 2 yl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1 octane b	0.69	1
32	bdb 3 benzyl thiophen 3 yl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1 octane b	0.69	1
33	bdb 3 cyclohexylmethyl thiophen 3 yl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2	0.69	1
34	bdb 3 endo 3 2 2 di 2 thienylethenyl 8 8 dimethyl 8 azoniabicyclo 3 2 1 octane bromi	0.69	1
35	bdb 3 endo 3 2 cyano 2 2 diphenylethyl 8 8 dimethyl 8 azoniabicyclo 3 2 1 octane bro	0.69	1
36	bdb 3 furan 3 ylmethyl phenyl carbamoyloxy 8 8 dimethyl 8 azonia bicyclo 3 2 1 octan	0.69	1
37	bdb 8 8 dimethyl 3 phenyl thiophen 2 ylmethyl carbamoyloxy 8 azonia bicyclo 3 2 1 oc	0.69	1
38	bdb 8 8 dimethyl 3 phenyl thiophen 3 ylmethyl carbamoyloxy 8 azonia bicyclo 3 2 1 oc	0.69	1
39	bdb 8 8 dimethyl 3 thiophen 3 yl thiophen 3 ylmethyl carbamoyloxy 8 azonia bicyclo 3	0.69	1
40	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl 3 methylfuran 2 yl methyl phenyl carbama	0.69	1
41	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl 3 methylthiophen 2 yl methyl phenyl carb	0.69	1
42	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl 4 bromobenzyl phenyl carbamate chembl238	0.69	1
43	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl 4 cyanobenzyl phenyl carbamate chembl391	0.69	1
44	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl 4 cyanobenzyl thiophen 3 yl carbamate ch	0.69	1
45	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl 5 methylthiophen 2 yl methyl phenyl carb	0.69	1
46	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl benzyl phenyl carbamate chembl237954	0.69	1
47	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl benzyl thiophen 2 yl carbamate chembl236	0.69	1
48	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl benzyl thiophen 3 yl carbamate chembl236	0.69	1
49	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl cyclohexylmethyl thiophen 3 yl carbamate	0.69	1
50	bdb 8 methyl 8 aza bicyclo 3 2 1 octan 3 yl furan 3 ylmethyl phenyl carbamate chembl	0.69	1

Showing top 50 of 96 compounds. Use the BiohacksAI search to explore all ACM2 modulators.

About ACM2 as a Drug Target

ACM2 (Muscarinic acetylcholine receptor M2) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 96 compounds with documented ACM2 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ACM2 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.