What compounds target ACM4?

BiohacksAI has identified 26 compounds that interact with ACM4 (Muscarinic acetylcholine receptor M4). Top compounds include: bdb atropen atropine, bdb chembl116590 cas 132 17 2 nsc 2344 benztropine, bdb mequitazine 3 10h phenothiazin 10 ylmethyl 1 azabicyclo 2 2 2 octan 1 ium zinc01, bdb chembl516641 hyperforin, bdb chembl2205836. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is ACM4 (Muscarinic acetylcholine receptor)?

ACM4 is Muscarinic acetylcholine receptor M4. It is a molecular target for 26 compounds documented in PubMed bioassay data.

ACM4

MOLECULAR TARGET

Muscarinic acetylcholine receptor M4

26 compounds

ACM4 (Muscarinic acetylcholine receptor M4) is targeted by 26 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting ACM4

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	bdb atropen atropine	1.79	5
2	bdb chembl116590 cas 132 17 2 nsc 2344 benztropine	1.39	3
3	bdb mequitazine 3 10h phenothiazin 10 ylmethyl 1 azabicyclo 2 2 2 octan 1 ium zinc01	1.10	2
4	bdb chembl516641 hyperforin	0.69	1
5	bdb chembl2205836	0.69	1
6	bdb chembl2205811	0.69	1
7	bdb n 2 3 fluorophenyl ethyl 8 aminopentacyclo 5 4 0 02 6 03 10 05 9 undecane chembl	0.69	1
8	bdb chembl2205812	0.69	1
9	bdb chembl2205813	0.69	1
10	bdb chembl2205823	0.69	1
11	bdb chembl2205825	0.69	1
12	bdb chembl1189234 chembl538300 11 benzyl 11 azahexacyclo 5 4 1 02 6 03 10 04 8 09 12	0.69	1
13	bdb chembl2205816	0.69	1
14	bdb 3 hydroxy 2 phenyl propionic acid 9 methyl 3 oxa 9 aza tricyclo 3 3 1 0 2 4 non	0.69	1
15	bdb 4 hydroxy 1 aza bicyclo 3 3 1 non 3 ene 3 carboxylic acid ethyl ester chembl3064	0.69	1
16	bdb djocicqnbmtmng	0.69	1
17	bdb exo 8 benzyloxymethyl 4 hydroxy 1 aza bicyclo 3 3 1 non 3 ene 3 carboxylic acid	0.69	1
18	bdb iczvktvmhvhoqi	0.69	1
19	bdb isoptpo hyoscine scopolamine	0.69	1
20	bdb 4 nitro benzoic acid 8 aza bicyclo 3 2 1 oct 6 yl ester chembl315428	0.69	1
21	bdb benzoic acid 8 aza bicyclo 3 2 1 oct 6 yl ester chembl84113	0.69	1
22	bdb cyclohexanecarboxylic acid 8 aza bicyclo 3 2 1 oct 6 yl ester chembl82754	0.69	1
23	bdb propionic acid 8 methyl 8 aza bicyclo 3 2 1 oct 6 yl ester chembl440138	0.69	1
24	bdb acetic acid 8 methyl 8 aza bicyclo 3 2 1 oct 6 yl ester 6 acetoxy 8 methyl 8 azo	0.69	1
25	bdb propionic acid 8 aza bicyclo 3 2 1 oct 6 yl ester chembl310558	0.69	1
26	bdb 8 aza bicyclo 3 2 1 octane 6 carboxylic acid methyl ester chembl64788	0.69	1

About ACM4 as a Drug Target

ACM4 (Muscarinic acetylcholine receptor M4) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 26 compounds with documented ACM4 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

ACM4 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.