CDK1
MOLECULAR TARGETcyclin dependent kinase 1
CDK1 (cyclin dependent kinase 1) is targeted by 16 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).
Compounds Targeting CDK1
Ranked by bioassay confidence score (PubChem active assay count × evidence quality).
| # | Compound | Confidence | Active Assays |
|---|---|---|---|
| 1 | kenpaullone | 2.64 | 13 |
| 2 | alsterpaullone | 2.40 | 10 |
| 3 | indirubin | 1.79 | 5 |
| 4 | Clofibrate | 1.39 | 3 |
| 5 | Fenofibrate | 1.39 | 3 |
| 6 | Sertraline | 1.10 | 2 |
| 7 | Cinnarizine | 1.10 | 2 |
| 8 | Clotrimazole | 1.10 | 2 |
| 9 | Rotenone | 1.10 | 2 |
| 10 | Apigenin 5,7,4'-trihydroxy-flavone, | 0.69 | 1 |
| 11 | chrysin | 0.69 | 1 |
| 12 | fisetin | 0.69 | 1 |
| 13 | Luteolin 5,7,3',4'-tetrahydroxy-flavone, | 0.69 | 1 |
| 14 | Quercetin | 0.69 | 1 |
| 15 | Sorafenib | 0.69 | 1 |
| 16 | sp600125 | 0.69 | 1 |
About CDK1 as a Drug Target
CDK1 (cyclin dependent kinase 1) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 16 compounds with documented CDK1 interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.
CDK1 inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.