What compounds target CHLE?

BiohacksAI has identified 33 compounds that interact with CHLE (Cholinesterase). Top compounds include: bdb huperzine a 13e 1 amino 13 ethylidene 11 methyl 6 azatricyclo 7 3 1 0 2 7 tridec, bdb 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14 hexaen 3 , bdb 7 fluoro 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14 , bdb hupriney hydrochloride huprine y hcl chembl536047, bdb rac 5 fluoro 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9. Each compound is ranked by evidence score derived from PubMed bioassay confidence and assay count.

What is CHLE (Cholinesterase)?

CHLE is Cholinesterase. It is a molecular target for 33 compounds documented in PubMed bioassay data.

CHLE

MOLECULAR TARGET

Cholinesterase

33 compounds

CHLE (Cholinesterase) is targeted by 33 compounds in the BiohacksAI evidence corpus, derived from PubMed bioassay data. Each compound is ranked by confidence score (log-normalized assay count × evidence quality).

Compounds Targeting CHLE

Ranked by bioassay confidence score (PubChem active assay count × evidence quality).

#	Compound	Confidence	Active Assays
1	bdb huperzine a 13e 1 amino 13 ethylidene 11 methyl 6 azatricyclo 7 3 1 0 2 7 tridec	1.61	4
2	bdb 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14 hexaen 3	1.39	3
3	bdb 7 fluoro 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14	1.10	2
4	bdb hupriney hydrochloride huprine y hcl chembl536047	1.10	2
5	bdb rac 5 fluoro 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9	1.10	2
6	bdb chembl4566976	0.69	1
7	bdb 11 amino 8 methyl 5 6 9 10 tetrahydro 6 10 methanocyclooctabenzo b 1 8 naphthyri	0.69	1
8	bdb 15 ethyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 14 hexaen 3 a	0.69	1
9	bdb 15 ethyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 15 hexaen 3 a	0.69	1
10	bdb 15 methyl 10 azatetracyclo 11 3 1 02 11 04 9 heptadeca 2 11 3 5 7 9 15 hexaen 3	0.69	1
11	bdb 7 chloro 15 methyl 10 azatetracyclo 11 3 1 0 2 11 0 4 9 heptadeca 2 4 9 5 7 10 1	0.69	1
12	bdb 9e 7 7 1 2 3 4 tetrahydroacridin 9 ylamino heptylamino 9 ethylidene 3 methylbicy	0.69	1
13	bdb 9e n1 7 1 2 3 4 tetrahydroacridin 9 ylamino heptyl 9 ethylidene 7 methylbicyclo	0.69	1
14	bdb chembl4072478	0.69	1
15	bdb chembl4438626	0.69	1
16	bdb chembl4462369	0.69	1
17	bdb chembl4469343	0.69	1
18	bdb chembl4471659	0.69	1
19	bdb chembl4558495	0.69	1
20	bdb chembl4591167	0.69	1
21	bdb chembl4741162	0.69	1
22	bdb chembl4743210	0.69	1
23	bdb chembl4744528	0.69	1
24	bdb chembl4748114	0.69	1
25	bdb chembl4754487	0.69	1
26	bdb chembl4782267	0.69	1
27	bdb chembl4782921	0.69	1
28	bdb chembl4788434	0.69	1
29	bdb chembl4794769	0.69	1
30	bdb n 2 azidoethyl 3 chloro 6 7 10 11 tetrahydro 12 ylamino 9 ethyl 7 11 methanocycl	0.69	1
31	bdb n 2 azidoethyl 3 chloro 6 7 10 11 tetrahydro 12 ylamino 9 methyl 7 11 methanocyc	0.69	1
32	bdb n 2 hydroxyethyl 3 chloro 6 7 10 11 tetrahydro 12 ylamino 9 ethyl 7 11 methanocy	0.69	1
33	bdb n 3 amino 7 chloro 15 methyl 10 azatetracyclo 11 3 1 0 2 11 0 4 9 heptadeca 2 4	0.69	1

About CHLE as a Drug Target

CHLE (Cholinesterase) is a well-characterized molecular target in biomedical research. BiohacksAI tracks 33 compounds with documented CHLE interaction from PubChem bioassay data, cross-referenced with PubMed clinical evidence. The confidence score reflects the log-normalized count of active PubChem assays, weighted by evidence quality from the BiohacksAI corpus.

CHLE inhibitors, activators, and modulators are of interest in research areas including longevity, metabolic health, and neurological function. Each compound profile includes evidence score, RCT count, human study ratio, research velocity, and domain relevance.